Simultaneous Isolation and Activation of T Cells – SIATTM

BioMag’s patent-pending SIATTM (Simultaneous Isolation and Activation of T cells) protocol allows T cells to be Simultaneously Isolated and Activated to permit downstream transduction and expansion of CAR-T cells.  Employing BioMag’s common-capture X-GRAFFETM ferrofluids, we have demonstrated isolation and activation of T cells from leukapheresis products in 1-Step.  Such T cells have been successfully transfected with a GFP plasmid with high efficiency and viability with cell expansions of 600-fold over 18 days have been achieved.